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During ultrasound evaluation of the bladder, we found it unnecessary to perform urethral catheterization beforehand.
Chemical burn is then introduced to the bladder mucosa using intravesical silver nitrate solution to disrupt the bladder glycosaminoglycan layer and allows cells to attach.
Urine seen within the catheter confirms its location within the bladder lumen.
In our experience, catheterization of athymic nude mice is more difficult than in C57 mice.
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We present a novel method for treating bladder cancer with intravesically delivered small activating RNA saRNA in an orthotopic xenograft mouse bladder tumor model.
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